Welcome to the Louisiana State University Single Cell Genomics project sponsored by National Science Foundation Instrument Development for Biological Research award DBI-1556000. This grant, “Nanoscale Laser Ablation Capture for Single Cell Genomics,” was made to the LSU Department of Chemistry research group of Prof. Kermit Murray to develop an instrument for localized sampling of genomic material from single cells in tissue. The instrument uses an atomic force microscope to image the tissue and high-precision tip-enhanced laser ablation to select material for quantification and sequencing. The material is sampled with high precision from individual cells in spatially selected regions. The project goals are construction of the laser ablation system, automated imaging and sample collection, and demonstration of the instrument with breast cancer tissue samples.
The results of the project will be disseminated using an array of social media platforms that are aimed at demonstrating the capabilities of the approach broadly to the general public. The social media platforms where you can find more information about this project (on-line to date) are
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